In Spite of Ourselves

In Spite of Ourselves is the 13th studio album of John Prine, featuring duets of classic country songs with various well-known female folk and alt-country vocalists, released in 1999.

The album was Prine’s first release since successfully battling throat cancer. The female duet partners include Iris DeMentConnie SmithLucinda WilliamsTrisha YearwoodMelba MontgomeryEmmylou HarrisDolores KeanePatty Loveless, and his wife, Fiona Prine.